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Plexison Validating Cell-based assays for Antibody-mediated rejection after renal transplantation

Validating Cell-based assays for Antibody-mediated rejection after renal transplantation

Associated Conditions

Antibody-Mediated Graft Rejection

Principal Investigator

Sponsor

Plexision

The purpose of this study is to evaluate whether new blood tests can detect rejection due to antibodies after kidney transplantation. Rejection occurs in some patients who receive a kidney transplant. In some cases, immune cells attack organs directly, leading to cellular rejection. At other times, immune cells make antibodies directed at the new organ, leading to antibody-mediated rejection. Each type of rejection requires a different type of treatment. Information obtained from these new blood tests can someday be combined with other available information to improve selection of the right medicine for the right patient. This can help to prevent and treat the different types of rejection in a timely manner. Plexision has developed tests to predict and diagnose cellular and antibody-mediated rejection. Investigators at your center and another center in the US have worked with Plexision to develop this study. Plexision will receive blood samples for testing, analyze results along with information about research subjects, and coordinate the administrative aspects of this study.

This study is currently enrolling.