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Lauren M. Sparks, PhD

Lauren M. Sparks, PhD

Associate Investigator at the Translational Research Institute for Metabolism and Diabetes.

Translational Research

Lauren Sparks

Overview

Dr. Lauren M. Sparks is an Investigator at the Translational Research Institute for Metabolism and Diabetes. Dr. Sparks pursues investigations on the topics of exercise response variation. Dr. Sparks is interested in understanding why some individuals do not respond favorably to exercise as a means of improving their metabolism and related co-morbidities. She aims to advance the field of exercise and type 2 diabetes and potentially shift the paradigm, allowing interventions to be targeted to those individuals most likely to benefit as well as identify novel approaches to treat those who do not. Dr. Sparks investigates the communication between muscle and fat tissue and how some individuals who are obese, but metabolically healthy, differ from those individuals who are obese and metabolically unhealthy. Prior to joining the TRI-MD, Dr. Sparks was a postdoctoral scientist at Maastricht University in the Netherlands from 2009-2012. She focused on exercise and mitochondrial function in muscle and brown adipose tissue. From 2006-2009, Dr. Sparks was a postdoctoral fellow at Pennington Biomedical Research Center in Baton Rouge, Louisiana with a focus on exercise and substrate metabolism in type 2 diabetes. Dr. Lauren Sparks was born in Patterson, Louisiana. She earned a B.S. in Zoology and a B.A. in Spanish in 2002 and continued on to earn her PhD in Molecular Biology in 2006 from Louisiana State University.

Articles

Skeletal muscle transcriptome response to a bout of endurance exercise in physically active and sedentary older adults.

American journal of physiology. Endocrinology and metabolism

2022

A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function

CIRCULATION

2021

The Metabolic Significance of Intermuscular Adipose Tissue: Is IMAT a Friend or a Foe to Metabolic Health?

DIABETES

2021

Prolonged Glucagon Infusion Does Not Affect Energy Expenditure in Individuals with Overweight/Obesity: A Randomized Trial

Obesity

2021

Twenty-four hour assessments of substrate oxidation reveal differences in metabolic flexibility in type 2 diabetes that are improved with aerobic training

DIABETOLOGIA

2021

A Metabolomic Signature of Glucagon Action in Healthy Individuals With Overweight/Obesity

JOURNAL OF THE ENDOCRINE SOCIETY

2021

An improvement in skeletal muscle mitochondrial capacity with short-term aerobic training is associated with changes in Tribbles 1 expression

PHYSIOLOGICAL REPORTS

2020

Plasma Myokine Concentrations After Acute Exercise in Non-obese and Obese Sedentary Women

FRONTIERS IN PHYSIOLOGY

2020

Individual Response Variation in the Effects of Weight Loss and Exercise on Insulin Sensitivity and Cardiometabolic Risk in Older Adults

FRONTIERS IN ENDOCRINOLOGY

2020

Targeting White Adipose Tissue with Exercise or Bariatric Surgery as Therapeutic Strategies in Obesity

BIOLOGY-BASEL

2019

Education & Training

Education

Louisiana State University, Baton Rouge, LA