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Centralized Core Services

Centralized Core Services

Overview

The Centralized Core provides services for all of AdventHealth Research Institute departments for internally and externally sponsored projects.


Contact Information

Centralized Core Services

Areas of Focus

  • Biostatistics
  • Health Economics
  • Centralized Laboratory
  • Medical Editing

Our Capabilities

Biostatistical or Health Economist (HEOR) support focuses on the following areas of service:

  • Step 1 (preliminary study design) – Advice regarding study design, sample size, variable selection and analysis options. 
  • Step 2 (advanced study design) – Review of draft research protocol with specific emphasis on the analysis section of protocol.
  • Step 3 (study implementation) – Advice regarding proper form for electronic collection of data, questionnaire construction or data acquisition. 
  • Step 4 (study completion) – Analysis and interpretation of results provided for supported studies. Written report including summary tables may be provided.  
  • Step 5 (publication)  – Statistical interpretation section of manuscripts will be reviewed for non-authored manuscripts. Authored articles will have statistical methodology section provided.

The medical editor serves as a bridge between researchers who create ideas and audiences who use them. The medical editor uses a didactic approach to support principle investigators and their research teams in submitting successful journal manuscripts or competitive grant proposals seeking NIH or organizational funding. 

  • For manuscripts, researchers and students are encouraged to first consult with Statistical Consulting Services early in the formulation of a research project, so that study design, primary objectives and analysis are specified correctly. Data elements must be collected in a format that is both manageable and conducive to the appropriate analysis.
  • When the manuscript is ready for editing, the medical editor and researcher will determine the level of editorial support needed to achieve a successful outcome, ranging from proofreading and polishing to substantive editing or post-peer review resubmission. 
  • For grant proposals, the medical editor is available to assist researchers in organizing the proposal components as well editing the research plan. Researchers are encouraged to contact the medical editor early in the grant preparation/writing process.
  • The medical editor also is available to help researchers enhance their PowerPoint presentations and polish their presentation skills. This support option is particularly helpful for researchers for whom English is a second language.
  • The laboratory is equipped with molecular biology and cytometric analysis instrumentation for cancer biomarker analysis and tumor tissue processing/pathological review. 
  • The core has the capability for sterile, viable circulating tumor cell capture using advanced high throughput FACS/flow cytometry analysis using a customized aseptic sorting Beckman Coulter MoFlo MDX FACS system. 
  • Equipment for biomarker molecular analyses includes freezer/refrigerator, MagPix molecular analyte array analyzer, CO2 Incubator, autoclave, Gel Logic 4000 pro DNA/protein imaging system, Zeiss Axio Observer 2A microscope and standard and invert Leitz phase contrast microscopes, Smart2Pure Water System, six-color MoFlo XDP Sterile high-speed flow FACS cytometer contained in a dedicated Class II-A laminar flow for aseptic cell sorting and circulating tumor cell isolation, four-color Accuri flow cytometer, BioRad Real Time PCR thermocycler, Stratagene Real Time PCR System, Cytospin centrifuge, LN2, gaseous and dry ice CO2 and 2 EVAC vacuum aspirators and hot plates, heat blocks, vortexes, sonicator, pH meter, and pipettors.