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BP42155 : BP42155: A Phase Ib/IIa, Randomized, Double Blind, Placebo-Controlled, Multiple Ascending Dose, Parallel-Group Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in P

NCT04639050

: BP42155: A Phase Ib/IIa, Randomized, Double Blind, Placebo-Controlled, Multiple Ascending Dose, Parallel-Group Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Patients With Prodromal or Mild to Moderate Alzheimer's Disease (Brainshuttle AD)

Associated Conditions

Alzheimers

Principal Investigator

Sponsor

Roche Diagnostics

Trontinemab is an experimental drug that is being developed for the possible treatment of AD. Trontinemab combines an anti-amyloid antibody with a brain shuttle module which helps to deliver the antibody to the brain. It works by preventing, blocking, and/or reducing the accumulation of beta amyloid plaques in the brain. The purpose of this study is to test the safety of trontinemab at different dose levels and to find out what effects, good or bad, trontinemab has on you and on early symptoms of AD.

This study is currently enrolling.