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A012103 Optimice-PCR: De-Escalation Of Therapy In Early-Stage TNBC Patients Who Achieve PCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy

NCT5812807

Optimice-PCR: De-Escalation Of Therapy In Early-Stage TNBC Patients Who Achieve PCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy

Associated Conditions

Breast Cancer

Principal Investigator

Sponsor

NCI/NCTN Alliance Group

This study is being done to answer the following question: Among patients with early-stage TNBC who achieve a pCR after preoperative chemotherapy in combination with pembrolizumab, will observation after surgery be as effective as completing 6 more months of pembrolizumab after surgery at preventing cancer from coming back? We are doing this study because we want to find out if observation is as good as the usual approach for your breast cancer. The usual approach is defined as care most people get for breast cancer

This study is currently enrolling.