Your study doctor has determined you have or have had a pulmonary embolism (PE). A PE is a blood clot in an artery or arteries in your lung. A clot can be life threatening if immediate action is not taken to resolve it. At this time, your doctor has decided that your clot should be treated to prevent damage to your heart and lungs and to help in your recovery. One possible treatment for PE is to remove the clot using a medical device that sucks the clot out of your body. This is called aspiration thrombectomy. During aspiration thrombectomy, a small tube (or catheter) is put into your blood vessel(s), either through your neck or groin, and navigated to the clotted (blocked) artery in your lung. Once the catheter reaches the clot, the doctor will use suction to remove the clot. The device that will be used for aspiration thrombectomy in this study is the Indigo Aspiration System.