Critical Care

Overview

Critical Care Research for COVID-19

The COVID-19 pandemic represents an unprecedented challenge for our hospitals and our community, with the state of Florida as one of the nation’s hotspots. As of February 1, 2021, more than 1,023,000 patients have been tested nationally across the AdventHealth enterprise. In Florida, AdventHealth has tested over 733,000 patients.

To meet the demands of COVID-19 treatment options and clinical trials, AdventHealth Research Institute has engaged operational teams in the inpatient and outpatient settings to include medical oversight by a Physician Principal Investigator and an APRN/PA with prior infectious disease experience. Clinical research coordinators, medical assistants, pharmacists, lab techs, and program management support round out these multidisciplinary collaborative teams.

Our world-class team of researchers, clinical scientists and support staff is equipped to meet a wide array of research needs ranging from early-phase PoC/PoM trials to Phase I-III trials as well as RWE and HEOR. Research Services highlights include: PIs with extensive research and publications experience; CDA execution within 24 hours; access to local IRB with ability to use Central IRB; IRB approval completed within two weeks of submission; MSA to FPI turnaround of five days (COVID trials); remote monitoring with access to our electronic medical record; CRCs’ have experience with most EDC systems; and high staff retention rates of our RAs and RNs.

Contact Information

Critical Care Research Team

COVID-19ClinicalTrials@ahsonline.onmicrosoft.com

Featured Clinical Trials

Blood Purification with Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19: An Observational Study (PURIFY-OBS-1)

This study is currently enrolling.

You are being asked to take part in this research study because you have been admitted to an intensive care unit and have been diagnosed with severe COVID-19. COVID-19 is a respiratory illness caused by a SARS-CoV-2 virus that ...

NCT04401475

EDESA - A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 and SOC versus Placebo and SOC in Adult Hospitalized Patients with COVID-19

This study is currently enrolling.

The purpose of this study is to evaluate the clinical efficacy and safety of EB05 and Standard of Care vs. Standard of Care alone in adult hospitalized patients with COVID-19. This is a Phase II/III study conducted in two stage ...

View All Clinical Trials

Meet the Team

Amay Parikh, MD

Medical Director of NeuroICU, Critical Care Nephrologist & Neurointensivist

Full Bio

Eduardo Oliveira, MD

Physician Investigator

Jason C. Sniffen, DO, FACOI, FACP, FIDSA

Infectious Disease Specialist

Full Bio

Meet the Entire Team

Fighting COVID-19

PowerBI Pandemic Dashboard

To aid operations in the containment, mitigation, surge, and post-surge phases of the pandemic, AdventHealth developed the COVID-19 Pandemic Tracker, where all orders for COVID-19 tests and their results are curated in a big data server, allowing for near real-time reporting. AdventHealth collects data resulting from nasopharyngeal and saliva PCR testing, serology, and rapid antigen testing in our inpatient, outpatient, and ED facilities. COVID-19 testing volumes, positive patient census, and intervention utilization and outcomes are published every half hour on the Pandemic Tracker Microsoft PowerBI dashboard. Supplementary dashboards track COVID-19 patient demographic and clinical data, cohort unit capacity, lab turnaround times, supply chain, PPE and medication inventory and demand.

The RECOVER-19 Registry

The AdventHealth Research Institute initiated a registry study in order to collect and disseminate clinical and laboratory data for research for all patients tested in the Central Florida Division. Soon to be expanded to the entire AdventHealth enterprise, the registry was developed under the IRB approved protocol named “Registry and Biorepository of COVID-19 for AdventHealth Enterprise” (RECOVER-19 - AdventHealth IRBNet # 1590483). This protocol can support feasibility queries and is approved for data collection for the next five years.

RECOVER-19 is a real-world data (RWD) registry that includes clinical data on all patients tested for Coronavirus Disease 2019 (COVID-19) (both positive and negative) at AdventHealth CFD beginning January 1, 2020. The registry includes zip codes; demographic information; all personal medical history; and COVID-19 encounter clinical information such as type of encounter, length of stay, presenting symptoms, outcome, medication history during all inpatient visits and post-discharge, all procedures and diagnoses, and approximately 80 selected labs.

About the Facility

The Critical Care Research team is based out of AdventHealth's Orlando campus, which provides participants access to state of the art care and research opportunities.