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Clinical Trial Search Results
EXPET: Dynamic in vivo PET imaging and ex vivo biopsies from skeletal muscle and adipose tissue to investigate the effects of exercise on insulin resistance and mitochondrial energetics in type 2 diabetes
This study is currently enrolling.
The overall aim of this study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).
FABULINUS: A 52-week randomized, double-blind, placebo controlled, multi-center Phase 2b study with a 52-week blinded extension assessing safety and efficacy of frexalimab, a CD40L-antagonist monoclonal antibody, for preservation of pancreatic beta-cell function in adults and adolescents with newly diagnosed type 1 diabetes on insulin therapy.
This study is currently enrolling.
Study Purpose: The study is aimed to evaluate an investigational drug, frexalimab, for preservation of pancreatic beta cell function in adults and adolescents that have been newly diagnosed with Type 1 Diabetes and started on i ...
FINE-ONE: A parallel-group, randomized, prospective, interventional, double-blind, multicenter global Phase 3 study to investigate the efficacy and safety of Finerenone versus placebo, in addition to standard of care, in participants with chronic kidney disease and type 1 diabetes
This study is currently enrolling.
Study Purpose: The aim of the study is to demonstrate efficacy of Finerenone when compared to placebo, in addition to standard of care, in delaying the progression of chronic kidney disease (CKD) in participants with CKD and T1 ...
FURMO-002: A Phase 1b Dose Escalation and Dose Expansion Study Evaluating the Safety, Pharmacokinetics, and Antitumor Activity of Furmonertinib in Patients with Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) with Activating EGFR or HER2 Mutations, Including Exon 20 Insertion Mutations
This study is currently enrolling.
The purpose of this study is to learn about how the study drug, furmonertinib, works in patients with NSCLC who have a mutation in the EGFR or HER2 gene and how it may help them. For patients with this type of NSCLC, the study ...
GLADIATOR: A phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of 400 mg twice a day oral ladarixin in patients with new-onset type 1 diabetes and a low residual β-cell function at baseline.
This study is currently enrolling.
The purpose of this study is to check and collect data of how the body absorbs, distributes and gets rid of the study drug in the blood during the first cycle of LDX0319 study treatment. These data will help improve knowledge a ...
GOG 3069 Phase 2 Study of Alpelisib and Fulvestrant for PIK3CA-mutated Estrogen Receptor (ER)-positive Endometrioid Endometrial Cancers
This study is currently enrolling.
The purpose of this study is to find out if the combination of the drugs alpelisib and fulvestrant is better or worse than the usual approach for your type of cancer. The usual approach is defined as care most people get for e ...
GTM-102: A Phase 3 Randomized Controlled Trial of Post-Surgical Stereotactic Radiotherapy (SRT) versus Surgically Targeted Radiation Therapy (STaRT) with Gamma Tile for Treatment of Newly Diagnosed Metastatic Brain Tumors
This study is currently enrolling.
The purpose of this research study is to compare surgical tumor removal followed by stereotactic radiotherapy (SRT) to surgical tumor removal followed by radiation therapy delivered by surgically implanted GammaTiles.
HYPERION A Phase 3, Randomized, Doubleblind, Placebo-controlled Study to Evaluate Sotatercept When Added to Background Pulmonary Arterial
Hypertension (PAH) Therapy in Newly Diagnosed Intermediate-and High-risk PAH Patients
Hypertension (PAH) Therapy in Newly Diagnosed Intermediate-and High-risk PAH Patients
This study is currently enrolling.
Pulmonary arterial hypertension (PAH) is a disease affecting the blood vessels of the lungs. PAH leads to increased pressure in the blood vessels of the lungs which further leads to straining of the right side of the heart. You ...
Impact of BFR Protocol on postop Elbow ROM
This study is currently enrolling.
The purpose of the study is to compare the elbow range of motion (ROM) at 3 months after elbow fracture surgery between the conventional BFR protocol versus individualized protocol based on the muscle oxygenation (SPO2) le ...