Clinical Trial Search Results
Predicting non-union and optimizing fracture fixation by studying osteon properties at the non-union using Micro-CT and micro finite element analysis
This study is currently enrolling.
The purpose of the study is to identify the differences between individual osteon geometrical properties (size, distribution, density) and microscale mechanical properties of non-union and healthy bones utilizing micro finite e ...
PRESERVE-003: Phase 3, Two-stage, Randomized Study of ONC-392 Versus Docetaxel in Metastatic Non-Small Cell Lung Cancers that Progressed on PD-1/PD-L1 Inhibitors
This study is currently enrolling.
The main purpose of the study is to determine whether the study drug, ONC-392, is safe and well tolerated, and whether it is effective in treating lung cancer, in comparison with a standard of care chemotherapy drug, docetaxel. ...
Prevail Therapeutics, Inc. / A Phase 1/2 Ascending Dose Study to Evaluate the Safety and Effects on Progranulin Levels of PR006A in Patients with Fronto-Temporal Dementia with Progranulin Mutations
This study is currently enrolling.
Fronto-temporal dementia or frontotemporal lobar degeneration refers to a group of disorders caused by progressive cell loss in the brain's frontal lobes or its temporal lobes. These areas of the brain play a significant r ...
Prevail Therapeutics, Inc. A Phase 1/2a Open-Label, Ascending Dose Study to Evaluate the Safety and Effects of PR001A in Patients with Parkinson’s Disease with at Least One GBA1 Mutation
This study is currently enrolling.
You are being asked to consider whether you would like to participate in a clinical research study (also known as a clinical trial) of a study drug called PR001A because you have Parkinson’s disease. PR001A is being developed f ...
Prognostic Values of Near-Infrared Spectroscopy measurement of Muscle Oxygen Saturation in detecting Deep Vein Thrombosis Compared to Doppler Ultrasound
This study is currently enrolling.
The purpose of the study is to measure prognostic values of muscle SPO2 using NIRS in detecting DVT using Doppler Ultrasound.
Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse™ Bone Graft With an Intervertebral Body Fusion Device and Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine
This study is currently enrolling.
The purpose of this study is to evaluate the Infuse™ Bone Graft in combination with other spinal devices and autograft bone (your own bone) to see if it is safe and effective when used in a TLIF surgery. Two different amounts o ...
Quantitative and Qualitative In Vitro Evaluation of Emerging Bioengineered Scaffolds for Rotator Cuff Repair
This study is currently enrolling.
The purpose of the study is to investigate the effect of each scaffold on tendon cell attachment and proliferation in vitro in a bioreactor.
Randomized controlled Phase 2b clinical trial to evaluate the safety and efficacy of TVI-Brain-1 combined with conformal radiotherapy and temozolomide compared to standard therapy as a treatment for newly diagnosed O6-methylguanine methyltransferase negative (MGMT unmethylated) grade 4 astrocytoma (glioblastoma multiforme; glioblastoma; GBM).
This study is currently enrolling.
This clinical trial is being performed because there is a need for safer and more effective treatments for glioblastomas. The purpose of this specific clinical study is to determine how safe and effective TVI-Brain-1 would be a ...
Randomized Trial on Hybrid vs Non-Hybrid ESD for Colorectal Polyps
This study is currently enrolling.
We invite you to take part in a research study because you have colorectal polyp and are being treated here at AdventHealth Orlando. A clinical trial (research study) is done when researchers (investigators) are trying to disco ...