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BP43176 A PHASE 1B, ADAPTIVE, MULTI-CENTER, RANDOMIZED, DOUBLE BLIND, PLACEBOCONTROLLED, PARALLEL DESIGN STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF RO7486967 IN PARTICIPANTS WITH EARLY IDIOPATHIC PARKINSON&rsqu

NCT05924243

A PHASE 1B, ADAPTIVE, MULTI-CENTER, RANDOMIZED, DOUBLE BLIND, PLACEBOCONTROLLED, PARALLEL DESIGN STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF RO7486967 IN PARTICIPANTS WITH EARLY IDIOPATHIC PARKINSON’S DISEASE

Associated Conditions

Parkinsons

Principal Investigator

Sponsor

Roche Diagnostics

The purpose of this study is to investigate what happens to RO7486967 once it is in the body, what RO7486967 does to the body, and to compare the effects (good or bad) of RO7486967 versus placebo on the inflammation in the brain and on Parkinson’s disease symptoms. In this study, participants will get either RO7486967 or placebo. A placebo is a pill or medicine that looks like a drug but has no active medicinal ingredients that can have an effect on your health. Placebos are commonly used in studies to see if the effects experienced by participants while taking a study treatment are really the result of the treatment instead of other causes. Approximately 48 to 72 people with Parkinson’s disease will take part in this study.
RO7486967 is an experimental drug. Health Authorities (like the U.S. Food and Drug Administration and European Medicines Agency) have not approved RO7486967 for the treatment of Parkinson’s disease and it has not been tested in people with Parkinson’s disease before this study.

This study is currently enrolling.