Cancer Research Institute
Clinical Trials
Phase 1 First-in-Human Study of Leukocyte Immunoglobulin-Like Receptor B2 (LILRB2) Inhibitor Monoclonal Antibody (mAb) JTX8064, as Monotherapy and in Combination with a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, in Adult Subjects with Advanced Refractory Solid Tumor Malignancies
A medical research study for participants who have been diagnosed with a solid tumor (i.e. cancer) and currently, the tumor is unresponsive to approved treatments, approved treatments are worsening the symptoms or the participa ...
Phase 3 Accelerated BEP Trial: A randomized phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumors.
This study will look to enroll Participants who have been diagnosed with having a germ cell tumor (GCT). The overall goal of this study is to determine whether accelerated BEP will be effective and well-tolerated for patients w ...
Phase III Randomized Trial of DFP-10917 vs. Non-Intensive Reinduction (LoDAC, Azacitidine Decitabine, Venetoclax combination regimens) or Intensive Reinduction (High and Intermediate Dose Cytarabine Regimens) for Acute Myelogenous Leukemia Patients in Second, Third, or Fourth Salvage.
This study will investigate whether a new experimental treatment, DFP-10917, will be an effective and safe treatment option for patients with relapsed/refractory acute myelogenous leukemia (AML). The purpose of this study is to ...
Prospective Registry for Colorectal Cancer: International Watch and Wait Database
This research is being done as part of a larger international database for 'Watch and Wait' rectal cancer patients. Currently, the 'Watch and Wait' treatment shows promising results worldwide, however furthe ...
Sentinel Lymph Node Endometrial Cancer Trial: A Prospective Multicenter International Single-Arm Observational Trial (SELECT)
We are doing this study to find out how often your type of cancer comes back (recurs) after the standard treatment. We also want to see how often the standard treatment results in a buildup of fluid and swelling in your legs (l ...
Treatment of Bone Marrow Failure, Post Allogeneic Bone Marrow Transplant,w ith CD34+ Cell-Enriched Hematopoietic Stem Cell Infusion (Miltenyi Biotec's CliniMACS CD34 Reagent System) A HDE Treatment Protocol
[Shell Only] - HUD/CUD.
You are being asked to take part in this research study because you have Systemic Juvenile Idiopathic Arthritis (sJIA) which may cause joint swelling and pain, fever, or other symptoms affecting the whole body (such as rash, swelling of your lymph nodes, a large liver or spleen, or inflammation of the lining around your lungs or heart). The purpose of this research study is to compare the effectiveness of the study drug, tofacitinib, to placebo for treatment of signs and symptoms of sJIA.
You are being asked to take part in this research study because you have Systemic Juvenile Idiopathic Arthritis (sJIA) which may cause joint swelling and pain, fever, or other symptoms affecting the whole body (such as rash, sw ...