Critical Care
Clinical Trials
Blood Purification with Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19: An Observational Study (PURIFY-OBS-1)
This study is currently enrolling.
You are being asked to take part in this research study because you have been admitted to an intensive care unit and have been diagnosed with severe COVID-19. COVID-19 is a respiratory illness caused by a SARS-CoV-2 virus that ...
EDESA - A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 and SOC versus Placebo and SOC in Adult Hospitalized Patients with COVID-19
This study is currently enrolling.
The purpose of this study is to evaluate the clinical efficacy and safety of EB05 and Standard of Care vs. Standard of Care alone in adult hospitalized patients with COVID-19. This is a Phase II/III study conducted in two stage ...
A MASTER PROTOCOL ASSESSING THE SAFETY, TOLERABILITY, AND EFFICACY OF ANTI-SPIKE (S) SARS-COV-2 MONOCLONAL ANTIBODIES FOR THE TREATMENT OF HOSPITALIZED PATIENTS WITH COVID-19
COVID-19. The study drug targets the virus that causes COVID-19 and may make it harder for the virus to infect you. The goals of the study include seeing whether the drug can cause serious side effects, whether it lowers infect ...
A multicenter, randomized, placebo-controlled, pragmatic Phase 3 study investigating the efficacy and safety of rivaroxaban to reduce the risk of major venous and arterial thrombotic events, hospitalization and death in medically ill outpatients with acute, symptomatic COVID-19 infection
The purpose of this study is to see if the study drug, rivaroxaban, is safe and useful for reducing the risk of blood clots in subjects who are diagnosed with COVID-19 and who have additional conditions that increase their risk ...
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of AT-527 in Subjects with Moderate COVID-19
You are being asked to take part in a clinical research study of an oral drug called AT-527 (a direct-acting antiviral drug). AT-527 is an investigational drug, which means it has not been approved for the treatment of any dise ...
A randomized, double-blind, dose-ranging, placebo controlled, Phase 2a evaluation of the safety, tolerability, and pharmacokinetics of PLN-74809 in participants with acute respiratory distress syndrome (ARDS) associated with at least severe COVID-19
This research study is studying an investigational drug, PLN-74809 (“study drug”), as a possible treatment in participants with acute respiratory distress syndrome (ARDS) associated with at least severe COVID-19 as there are li ...
Inhaled RLF-100 for the Treatment of Severe COVID-19 without respiratory failure
The purpose of this research is to: To show whether the study drug RLF-100 along with standard of care is better than standard of care alone in preventing progression from Severe COVID-19 to Critical-COVID-19 with respiratory f ...