CASINO: Low-Carbohydrate Diet and SGLT2-Inhibitor to Achieve Moderate Ketosis in Healthy Volunteers
Principal Investigator
Sponsor
The purpose of this study is to test the hypothesis that a low-carbohydrate diet combined with an SGLT2-inhibitor is sufficient to induce moderate ketosis in healthy volunteers. To be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the following criteria: Study Duration: Up to 10 weeks Study Commitment: 1 screening visit (approximately 2-3 hours), 1 outpatient visit and a 29 day inpatient stay. Age: 18-60 years old Sex: Male & Female Conditions/Eligibility: Male and Female aged 18-60 BMI 21-35 kg/m2 Overall healthy adult Not a diabetic Study Procedures: Screening process, which includes informed consent process, demographics, vitals, physical exam, urinalysis, blood draw, dexa scan. 1 outpatient visit which consists of standardized meals and randomization 29 full day inpatient stay which includes blood draws, vital signs, urine collections, low-carb diet consumption and administration of study medication, indirect calorimetry, and wearing a CGM Compensation: Up to $10,000. Please call (407)303-7193 or fill out the Contact Form below for more information.