
Translational Research Institute
Clinical Trials
ABA: ABA-Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
This study is currently enrolling.
The purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.
ACES: Ace Inhibitors Combined with Exercise for Hypertensive Seniors
This study is currently enrolling.
The purpose of this research study is to see if regular exercise when combined with one of three commonly used high blood pressure medications can improve the physical abilities of older adults to perform their daily life activ ...
AVAIL: AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry
This study is currently enrolling.
Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that leads to many health complications. Many people have this disease and do not know it. There are no medications available to treat it. The purpose of this ...
BATSR: BAT as a therapeutic for the metabolic and cardiac dysfunction with senescence
This study is currently enrolling.
Aging results in impaired metabolism and cardiac health. A third of the population over 60 years of age has diabetes (elderly-onset diabetes), and an additional third of this population has prediabetes. There is also a higher p ...
CASINO: Low-Carbohydrate Diet and SGLT2-Inhibitor to Achieve Moderate Ketosis in Healthy Volunteers
This study is currently enrolling.
The purpose of this study is to test the hypothesis that a low-carbohydrate diet combined with an SGLT2-inhibitor is sufficient to induce moderate ketosis in healthy volunteers. To be enrolled in this study, you must meet certa ...
DREAM: Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM). An observational cohort study from the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)
This study is currently enrolling.
Study Purpose: The purpose of this research study is to find out how many people with acute pancreatitis develop diabetes. Risk factors for diabetes and the types of diabetes that occur after acute pancreatitis will also be st ...
EPIC: Transcriptomic and epigenetic characterization of the subcutaneous fat depots in PCOS women
This study is currently enrolling.
Polycystic ovary syndrome, or PCOS, is a hormonal condition where your reproductive hormones are out of balance. PCOS is also associated with an increased risk to become obese and a male-like fat tissue distribution in women (a ...
EXPET: Dynamic in vivo PET imaging and ex vivo biopsies from skeletal muscle and adipose tissue to investigate the effects of exercise on insulin resistance and mitochondrial energetics in type 2 diabetes
This study is currently enrolling.
The overall aim of this study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).
FIND-CKD: A randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase 3 study to investigate the efficacy and safety of FInerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease.
This study is currently enrolling.
Study Purpose: To determine the safety and efficacy of Finerenone along with standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease. To be enrolled in this study, you must me ...