Paul M. Coen, PhD

Paul M. Coen, PhD

Associate Investigator at the Translational Research Institute

Translational Research

Paul M. Coen

Overview

Dr. Paul Coen is an Associate Investigator at the Translational Research Institute, AdventHealth Orlando.

Paul’s research program is supported by the National Institutes of Health (NIH) and is broadly focused on elucidating the role of skeletal muscle mitochondrial energetics in the pathophysiology’s associated with aging and obesity.
Paul’s postdoctoral training was in the area of muscle metabolism under the mentorship of Dr. Bret Goodpaster at the University of Pittsburgh’s Division of Endocrinology and Metabolism (2008-2010). His postdoctoral work resulted in authorship on numerous peer-reviewed publications in high impact journals such as the Journal of Clinical Investigation, Diabetes, and Diabetes Care.

Originally hailing from Dublin, Ireland, Paul made the jump across the pond to study for a PhD in Exercise Physiology at Purdue University, which he completed in 2008. Prior to this, he completed an M.S. in Vascular Biology at the Vascular Health Research Center (VHRC) at Dublin City University (2004), and received his initial didactic and laboratory-based training with a B.Sc. in Bioanalytical Science from the Institute of Technology, Tallaght, Ireland (2000).

Articles

Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans

CELL REPORTS

2023

Exercise and ageing impact the kynurenine/tryptophan pathway and acylcarnitine metabolite pools in skeletal muscle of older adults

JOURNAL OF PHYSIOLOGY-LONDON

2023

The Study of Muscle, Mobility and Aging (SOMMA): A Unique Cohort Study About the Cellular Biology of Aging and Age-related Loss of Mobility

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

2023

Skeletal muscle transcriptome response to a bout of endurance exercise in physically active and sedentary older adults.

American journal of physiology. Endocrinology and metabolism

2022

Microphysiological system for studying contractile differences in young, active, and old, sedentary adult derived skeletal muscle cells

AGING CELL

2022

Skeletal muscle transcriptome response to a bout of endurance exercise in physically active and sedentary older adults

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

2022

State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future Directions.

Comprehensive Physiology

2022

Mitochondrial Energetics in Skeletal Muscle Are Associated With Leg Power and Cardiorespiratory Fitness in the Study of Muscle, Mobility and Aging

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

2022

A New Approach to Understanding Cancer-Related Fatigue: Leveraging the 3P Model to Facilitate Risk Prediction and Clinical Care

Cancers

2022

NAD(+) and human muscle health

NATURE AGING

2022

More Publication Information

Education & Training

Education

Purdue University, West Lafayette, IN

Fellowship

University of Pittsburgh School of Medicine

Associated Clinical Trials