Neuroscience Research Institute
Clinical Trials
A Randomized, Double-blind, Placebo-controlled, 12-month Phase 3 Study to Evaluate the Effect of Venglustat on Neuropathic and Abdominal Pain in Male and Female Adults with Fabry Disease who are Treatment-naïve or Untreated for
At least 6 Months
At least 6 Months
This study is currently enrolling.
The purpose of the study is to evaluate daily oral doses of the study drug called venglustat compared to placebo: what is the effectiveness (how well it works) on symptoms of the Fabry disease, mainly neuropathic pain and abdom ...
Assessment of Safety and Efficacy of Exablate Blood-Brain Barrier Disruption for the Treatment of Patients with Probable Alzheimer’s Disease
This study is currently enrolling.
The result of this study will help us determine whether blood-brain barrier disruption (BBBD) with Exablate is a safe procedure in the brains of patients with Alzheimer’s Disease. The purpose of this study is to: Test the safe ...
Isolation of Tumor Cells, Cancer Stem Cells and
Human Neuronal Stem Cells from Human Brain Tumor Tissue for Analysis of Cancer Stem Cell Markers’ Expression in Cellular Differentiation and Self-renewal for Studying the Effectiveness of Cancer Therapy with Subsequent Identification of Exosomal Biomarkers for Early Diagnostic Purposes
Human Neuronal Stem Cells from Human Brain Tumor Tissue for Analysis of Cancer Stem Cell Markers’ Expression in Cellular Differentiation and Self-renewal for Studying the Effectiveness of Cancer Therapy with Subsequent Identification of Exosomal Biomarkers for Early Diagnostic Purposes
This study is currently enrolling.
The purpose of this clinical trial is to collect and study brain tumor samples to help understand why the tumor grows back and to seek new ways to treat it.
LONG-TERM FOLLOW-UP STUDY OF PATIENTS WITH SPINAL MUSCULAR ATROPHY RECEIVING RISDIPLAM TREATMENT
This study is currently enrolling.
The main purpose of this study is to follow patients receiving Evrysdi for a long time. This will add to the body of evidence about the safety and effectiveness of Evrysdi.
MSBASE: An international registry dedicated to evaluating outcomes data in multiple sclerosis (MS) and other neuroimmunological diseases (NIDs)
This study is currently enrolling.
The MSBase Registry is a research registry. Research registries are also known as a research databases. They collect information about lots of people, often who all have the same health condition. The objective of the MSBase Re ...
Phase 1/2a Open-Label Ascending Dose Study to Evaluate the Safety and Effects of LY3884961 in Patients with Parkinson’s Disease with at Least One GBA1 Mutation (PROPEL)
This study is currently enrolling.
Parkinson’s disease is a slowly progressive and disabling disease of the central nervous system that causes problems with movement, such as shaking, stiffness, slow movement, and difficulty walking. Patients may also experience ...
Prevail Therapeutics, Inc. / A Phase 1/2 Ascending Dose Study to Evaluate the Safety and Effects on Progranulin Levels of PR006A in Patients with Fronto-Temporal Dementia with Progranulin Mutations
This study is currently enrolling.
Fronto-temporal dementia or frontotemporal lobar degeneration refers to a group of disorders caused by progressive cell loss in the brain's frontal lobes or its temporal lobes. These areas of the brain play a significant r ...
Prevail Therapeutics, Inc. A Phase 1/2a Open-Label, Ascending Dose Study to Evaluate the Safety and Effects of PR001A in Patients with Parkinson’s Disease with at Least One GBA1 Mutation
This study is currently enrolling.
You are being asked to consider whether you would like to participate in a clinical research study (also known as a clinical trial) of a study drug called PR001A because you have Parkinson’s disease. PR001A is being developed f ...
Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse™ Bone Graft With an Intervertebral Body Fusion Device and Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine
This study is currently enrolling.
The purpose of this study is to evaluate the Infuse™ Bone Graft in combination with other spinal devices and autograft bone (your own bone) to see if it is safe and effective when used in a TLIF surgery. Two different amounts o ...