Translational Research Institute
Clinical Trials
TARGET-NASH: A 5-year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepatitis
This study is currently enrolling.
TARGET-NASH is a longitudinal observational cohort study of patients being managed for NASH or NAFL in clinical practice. TARGET-NASH will create a carefully maintained, actively monitored research registry of patients with NAF ...
TRIALNET: Natural History Study of the Development of Type 1 Diabetes
This study is currently enrolling.
You are being asked to be in a research study called the TrialNet Natural History Study of the Development of Type 1 Diabetes. As you know, TrialNet is an international research group dedicated to the study, prevention and earl ...
TRIPLE G: A Randomized, Double-Blind, Phase 1 Study to Investigate the Effect of LY3437943 versus Placebo on Calorie Intake and Energy Expenditure in Participants with Obesity Under Calorie Restriction
This study is currently enrolling.
Study Purpose: The purposes of this study are to look at the effect of the study drug compared to placebo (a drug that looks like the study drug but has no active medicine) on calorie intake, different uses of energy in the bod ...
SOUL - Semaglutide cardiovascular outcomes trial in patients with type 2 diabetes
We are doing this study to look at whether the study medicine (semaglutide) has a positive effect on heart disease in patients that have type 2 diabetes. This will be done by comparing the study medicine (semaglutide) against p ...
ABA: ABA-Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
The purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.
ACES: Ace Inhibitors Combined with Exercise for Hypertensive Seniors
The purpose of this research study is to see if regular exercise when combined with one of three commonly used high blood pressure medications can improve the physical abilities of older adults to perform their daily life activ ...
EPIC: Transcriptomic and epigenetic characterization of the subcutaneous fat depots in PCOS women
Polycystic ovary syndrome, or PCOS, is a hormonal condition where your reproductive hormones are out of balance. PCOS is also associated with an increased risk to become obese and a male-like fat tissue distribution in women (a ...
FIND-CKD: A randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase 3 study to investigate the efficacy and safety of FInerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease.
Study Purpose: To determine the safety and efficacy of Finerenone along with standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease. To be enrolled in this study, you must m ...
GILEAD: A Phase 1, Randomized, Single-blind, Placebo-controlled, Multiple-dose, Two-sequence, Cross-over Study to Evaluate the Effect of Ranolazine on Glucagon Secretion in Subjects with Type 2 Diabetes Mellitus, Followed by An Open-label, Single-dose, Exenatide Active-control Period
The primary purpose of this study is to understand the reasons why Ranolazine may potentially treat patients with T2DM. Ranolazine has been shown to block glucagon and therefore results in a lowering of blood glucose levels. Th ...