Translational Research Institute
Clinical Trials
FIND-CKD: A randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase 3 study to investigate the efficacy and safety of FInerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease.
Study Purpose: To determine the safety and efficacy of Finerenone along with standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease. To be enrolled in this study, you must m ...
GILEAD: A Phase 1, Randomized, Single-blind, Placebo-controlled, Multiple-dose, Two-sequence, Cross-over Study to Evaluate the Effect of Ranolazine on Glucagon Secretion in Subjects with Type 2 Diabetes Mellitus, Followed by An Open-label, Single-dose, Exenatide Active-control Period
The primary purpose of this study is to understand the reasons why Ranolazine may potentially treat patients with T2DM. Ranolazine has been shown to block glucagon and therefore results in a lowering of blood glucose levels. Th ...
GluCog: Glycemic Variability and Fluctuations in Cognitive Status in Adults with Type I Diabetes
The purposes of this study is to understand how thinking, emotions, and blood glucose fluctuate over hours and days in people with type I diabetes. Study Commitment: 1 Month Aged ≥ 18 years Sex: Male and Female Conditions/Eligi ...
HONEY: Development of novel biomarkers for the early diagnosis of type 1 diabetes
The purpose of this study is to identify novel biomarkers in the early stage of Type 1 Diabetes as well as to follow disease progression in individuals with early onset T1D. To be enrolled in this study, you must meet certain ...
MATPET: Dynamic PET imaging in skeletal muscle and adipose tissue to explore mechanisms of peripheral glucose uptake in African American, Hispanic, and Caucasian Women
Study Purpose: The objective of this study is to obtain a better understanding between skeletal muscle characteristics and the ability to metabolize glucose. AdventHealth is seeking African American, Hispanic and Caucasian wome ...
MODIFY: A Case-Control, Observational, Proof of Mechanism Study to Define Microbiome-Mediated Gut Dysfunction Across the Spectrum of Non-Alcoholic Fatty Liver Disease.
This study is being done to understand if the bacteria that are in your colon (the gut microbiome) get into the cells of the intestinal wall in people with fatty liver or fibrosis compared to people with healthy livers. When th ...
NAD-flux: Measurement of NAD+ Synthesis in Human Skeletal Muscle
Nicotinamide adenine dinucleotide (NAD) is a vitally important substance that is found in all cells of the body. Elevated levels of NAD are linked to health and well-being. The key objective of this pilot research study is to ...
PIONEER 4: A Study Investigating the Efficacy and Safety of Oral Semaglutide versus Liraglutide and versus Placebo in Subjects with Type 2 Diabetes Mellitus
Before a new medicine can be approved for use in humans, it is necessary to confirm that it is safe and effective. This is done by carrying out studies such as this one. The study product semaglutide is being developed for trea ...
RECODE: Researching Covid Outcomes in Diabetes
We invite you to take part in a research study because you have previously had a confirmed diagnosis for COVID-19 (the new coronavirus) disease. You have recovered, or are recovering from this disease, with no fever or cough wi ...